{"id":1002,"date":"2025-06-27T00:00:00","date_gmt":"2025-06-26T15:00:00","guid":{"rendered":"https:\/\/m.kawasaki-m.ac.jp\/mgm-lyso\/?p=1002"},"modified":"2025-07-14T16:48:55","modified_gmt":"2025-07-14T07:48:55","slug":"%e6%8e%b2%e8%bc%89%e6%83%85%e5%a0%b1%ef%bc%88%e8%ab%96%e6%96%87%ef%bc%89-5","status":"publish","type":"post","link":"https:\/\/m.kawasaki-m.ac.jp\/mgm-lyso\/?p=1002","title":{"rendered":"\u63b2\u8f09\u60c5\u5831\uff08\u8ad6\u6587\uff09"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>\u7d30\u80de\u5185\u306eLyso-Gb3\u306f\u30e0\u30b3\u30ea\u30d4\u30c9\u30fc\u30b7\u30b9II\/III\u578b\uff08I-cell\u75c5\uff09\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3068\u306a\u308b<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30e0\u30b3\u30ea\u30d4\u30c9\u30fc\u30b7\u30b9II\/III\u578b\uff08I-cell\u75c5\uff09\u306f\u3001\u7d30\u80de\u5185\u306e\u30e9\u30a4\u30bd\u30be\u30fc\u30e0\u9175\u7d20\u306e\u8f38\u9001\u969c\u5bb3\u306b\u8d77\u56e0\u3059\u308b\u30e9\u30a4\u30bd\u30be\u30fc\u30e0\u75c5\u3067\u3059\u3002\u7d30\u80de\u5185\u306b\u306f\u69d8\u3005\u306a\u672a\u5206\u89e3\u57fa\u8cea\u304c\u84c4\u7a4d\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u304a\u308a\u3001\u30e0\u30b3\u591a\u7cd6\u75c7\u3084\u30b9\u30d5\u30a3\u30f3\u30b4\u30ea\u30d4\u30c9\u30fc\u30b7\u30b9\u3068\u3082\u5171\u901a\u3057\u305f\u81e8\u5e8a\u75c7\u72b6\u3092\u5448\u3057\u307e\u3059\u3002\u6211\u3005\u306f\u672c\u75be\u60a3\u306b\u304a\u3044\u3066Lyso-Gb3\u304c\u7d30\u80de\u5185\u306b\u84c4\u7a4d\u3057\u3066\u3044\u308b\u4e8b\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u672c\u75be\u60a3\u306e\u539f\u56e0\u907a\u4f1d\u5b50<em>GNPTAB<\/em>\u3092\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u3057\u305f\u7d30\u80de\u682a\u306b\u304a\u3044\u3066Lyso-Gb3\u304c\u4e0a\u6607\u3057\u3001\u60a3\u8005\u76ae\u819a\u7dda\u7dad\u82bd\u7d30\u80de\u306b\u304a\u3044\u3066\u3082\u4e0a\u6607\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u60a3\u8005\u76ae\u819a\u7dda\u7dad\u82bd\u7d30\u80de\u306b\u84c4\u7a4d\u3057\u305fLyso-Gb3\u306f\u6211\u3005\u304c\u958b\u767a\u3057\u305f\u9175\u7d20\u88dc\u5145\u6cbb\u7642\u306b\u3088\u3063\u3066\u6e1b\u5c11\u3059\u308b\u3053\u3068\u3082\u78ba\u8a8d\u3057\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u60a3\u8005\u8840\u6f3f\u4e2d\u3067\u306fLyso-Gb3\u306e\u4e0a\u6607\u306f\u307f\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<br><br>\u30e0\u30b3\u30ea\u30d4\u30c9\u30fc\u30b7\u30b9II\/III\u578b\uff08I-cell\u75c5\uff09\u306b\u304a\u3044\u3066\u306f\u6709\u7528\u306a\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u304c\u5b58\u5728\u3057\u307e\u305b\u3093\u304c\u3001\u672c\u7814\u7a76\u6210\u679c\u304b\u3089\u3001\u7d30\u80de\u306b\u304a\u3051\u308bLyso-Gb3\u306f\u8a3a\u65ad\u3084\u6cbb\u7642\u52b9\u679c\u306e\u30de\u30fc\u30ab\u30fc\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u4eca\u5f8c\u3001\u75c5\u614b\u3068\u306e\u95a2\u9023\u3084\u6cbb\u7642\u958b\u767a\u306e\u4fc3\u9032\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<br><br><strong>Cellular Lyso-Gb3 Is a Biomarker for Mucolipidosis II.<\/strong><br>Terawaki S, Nakanishi H, Shibuya T, Sakai N, *Otomo T.<br><em><strong>Int J Mol Sci<\/strong><\/em>,\u00a02025,\u00a0<em>26<\/em>(13), 6275. doi.org\/10.3390\/ijms26136275<br><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40650054\/\" target=\"_blank\"><span style=\"text-decoration: underline;\"><span class=\"has-inline-color has-vivid-purple-color\">PMID: 40650054<\/span><\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7d30\u80de\u5185\u306eLyso-Gb3\u306f\u30e0\u30b3\u30ea\u30d4\u30c9\u30fc\u30b7\u30b9II\/III\u578b\uff08I-cell\u75c5\uff09\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3068\u306a\u308b \u30e0\u30b3\u30ea\u30d4\u30c9\u30fc\u30b7\u30b9II\/III\u578b\uff08I-cell\u75c5\uff09\u306f\u3001\u7d30\u80de\u5185\u306e\u30e9\u30a4\u30bd\u30be\u30fc\u30e0\u9175\u7d20\u306e\u8f38\u9001\u969c\u5bb3\u306b\u8d77\u56e0\u3059\u308b\u30e9\u30a4\u30bd\u30be\u30fc\u30e0\u75c5\u3067\u3059\u3002\u7d30\u80de\u5185&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-1002","post","type-post","status-publish","format-standard","hentry","category-3"],"_links":{"self":[{"href":"https:\/\/m.kawasaki-m.ac.jp\/mgm-lyso\/index.php?rest_route=\/wp\/v2\/posts\/1002","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/m.kawasaki-m.ac.jp\/mgm-lyso\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/m.kawasaki-m.ac.jp\/mgm-lyso\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/m.kawasaki-m.ac.jp\/mgm-lyso\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/m.kawasaki-m.ac.jp\/mgm-lyso\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1002"}],"version-history":[{"count":6,"href":"https:\/\/m.kawasaki-m.ac.jp\/mgm-lyso\/index.php?rest_route=\/wp\/v2\/posts\/1002\/revisions"}],"predecessor-version":[{"id":1015,"href":"https:\/\/m.kawasaki-m.ac.jp\/mgm-lyso\/index.php?rest_route=\/wp\/v2\/posts\/1002\/revisions\/1015"}],"wp:attachment":[{"href":"https:\/\/m.kawasaki-m.ac.jp\/mgm-lyso\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1002"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/m.kawasaki-m.ac.jp\/mgm-lyso\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1002"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/m.kawasaki-m.ac.jp\/mgm-lyso\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1002"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}